1. To screw someone or something, violently; in particular, to destroy a program or information irrecoverably. Often used in describing file-system damage. “So-and-so was running a program that did absolute disk I/O and ended up raping the master directory.”
2. To strip a piece of hardware for parts.
3. [CMU/Pitt] To mass-copy files from an anonymous ftp site. “Last night I raped Simtel's dskutl directory.”